Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8246475 | 0.91 | ALDH1A1 (0.58) | ALDH1A1PARP14PARP10SLC6A7MAPT | |
| SCHEMBL4761009 | 0.86 | MEN1 (0.56) | ALDH1A1TSHRKMT2AMAPTGAA | |
| SCHEMBL4763376 | 0.86 | SLC6A7 (0.48) | ALDH1A1TSHRKMT2APARP14PARP10 | |
| SCHEMBL4764201 | 0.85 | POLB (0.49) | ALDH1A1TSHRKMT2ASLC6A7MAPT | |
| SCHEMBL4761369 | 0.85 | POLB (0.52) | ALDH1A1TSHRKMT2APARP14PARP10 | |
| SCHEMBL8245894 | 0.85 | POLB (0.47) | ALDH1A1TSHRKMT2ASLC6A7MAPT | |
| SCHEMBL4763187 | 0.83 | SMN1; SMN2 (0.55) | ALDH1A1TSHRKMT2APARP14PARP10 | |
| SCHEMBL4762664 | 0.83 | POLB (0.56) | ALDH1A1TSHRKMT2APARP14PARP10 | |
| SCHEMBL4762861 | 0.83 | ALDH1A1 (0.64) | ALDH1A1HPGDTSHRKMT2AMAPT | |
| SCHEMBL4762716 | 0.82 | SMN1; SMN2 (0.51) | ALDH1A1TSHRKMT2ASLC6A7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007009635-A1 | PHENYL SUBSTITUTED PIPERAZINE-DERIVATIVES AS INHIBITORS OF PLAMINOGENIC ACTIVATOR INHIBITORS-I (PAI-I) | BAYER HEALTHCARE AG (DE) | 2007-01-25 | — | — | WO | disclosed |