Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.31 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30890455 | 0.85 | IMPDH2 (0.42) | IMPDH2PTPN1NR1H2NR1H3 | |
| SCHEMBL8249842 | 0.82 | VHL (0.36) | HDAC8 | |
| SCHEMBL8251212 | 0.81 | PEPD (0.38) | CRBNDDB1 | |
| SCHEMBL30445475 | 0.78 | IMPDH2 (0.41) | IMPDH2PTPN1HDAC8NR1H2NR1H3 | |
| SCHEMBL30890560 | 0.78 | IMPDH2 (0.39) | IMPDH2PTPN1HDAC8NR1H2NR1H3 | |
| SCHEMBL30992280 | 0.77 | IMPDH2 (0.44) | IMPDH2PTPN1HDAC8NR1H2NR1H3 | |
| SCHEMBL30180826 | 0.77 | HTR2C (0.39) | NPSR1 | |
| SCHEMBL30445328 | 0.75 | IMPDH2 (0.39) | IMPDH2PTPN1HDAC8NR1H2NR1H3 | |
| SCHEMBL30987635 | 0.75 | PTPN1 (0.40) | IMPDH2PTPN1HDAC8NR1H2NR1H3 | |
| SCHEMBL883144 | 0.75 | PTPN1 (0.40) | IMPDH2PTPN1HDAC8NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108632-A1 | HCV PROTEASE INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2008-05-08 | — | — | US | disclosed |
| US-20080108632-A1 | HCV PROTEASE INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108632-A1 | HCV PROTEASE INHIBITORS | SERPINB1, HAVCR2, RNASE1 | IMPDH2 884/4885PTPN1 1799/4885HDAC8 1884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.