Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 5/20 | 0.78 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Protirelin SCHEMBL33419 | 0.88 | TRHR (1.00) | TRHR | |
| Protirelin SCHEMBL10087946 | 0.88 | TRHR (1.00) | TRHR | |
| Protirelin SCHEMBL16091769 | 0.88 | TRHR (1.00) | TRHR | |
| Protirelin SCHEMBL10087855 | 0.88 | TRHR (1.00) | TRHR | |
| SCHEMBL14028661 | 0.88 | TRHR (0.78) | TRHRDPP4 | |
| SCHEMBL29539733 | 0.87 | TRHR (0.85) | TRHR | |
| SCHEMBL16088505 | 0.86 | TRHR (0.84) | TRHR | |
| SCHEMBL16072685 | 0.86 | TRHR (0.84) | TRHR | |
| Protirelin SCHEMBL1007386 | 0.85 | TRHR (0.91) | TRHR | |
| Protirelin SCHEMBL4406163 | 0.85 | TRHR (0.93) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006096829-A2 | THYROTROPIN-RELEASING HORMONE ANALOGS AND METHOD OF USE | ROGER WILLIAMS HOSPITAL (US) | 2006-09-14 | — | — | WO | disclosed |