SCHEMBL825264

SCHEMBL825264

CCCCCCCC/C(=C(\N)Cc1ccccn1)N(Cc1ccccn1)Cc1ccccn1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.41
KDM4E B2RXH2 2/20 0.41
LMNA P02545 2/20 0.41
HTT P42858 2/20 0.41
USP2 O75604 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
NPC1 O15118 1/20 0.41
HSP90AA1 P07900 1/20 0.41
RAB9A P51151 1/20 0.41
F2 P00734 1/20 0.39
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
HRH1 P35367 1/20 0.38
HDAC1 Q13547 2/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
MAPT P10636 2/20 0.38
LIN28A Q9H9Z2 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1332881 1.00 SMN1; SMN2 (0.41) SMN1; SMN2KDM4ELMNAHTTUSP2
SCHEMBL825216 0.77 TDP1 (0.45) SMN1; SMN2KDM4ELMNANPC1RAB9A
SCHEMBL10602330 0.74 GRIN2D (0.56) SMN1; SMN2KDM4ELMNAHTTF2
SCHEMBL11234921 0.73 LMNA (0.49) SMN1; SMN2KDM4ELMNAHTTUSP2
SCHEMBL6911822 0.71 LMNA (0.48) SMN1; SMN2KDM4ELMNAHTTUSP2
SCHEMBL7890898 0.71 HRH1 (0.54) SMN1; SMN2LMNANPC1RAB9AHRH1
SCHEMBL7890891 0.71 HRH1 (0.54) SMN1; SMN2LMNANPC1RAB9AHRH1
SCHEMBL30782564 0.69 LMNA (0.46) SMN1; SMN2KDM4ELMNAHTTUSP2
SCHEMBL10574137 0.69 CNR2 (0.47) SMN1; SMN2KDM4EMAPTNPSR1CYP1A2
SCHEMBL2189143 0.69 TRPM8 (0.47) SMN1; SMN2LMNAHTTF2NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9593232-B2 Liquid hardening OMG UK TECHNOLOGY LTD. (GB) 2017-03-14 US claimed
US-20140155525-A1 LIQUID HARDENING OMG UK TECHNOLOGY LTD. (GB) 2014-06-05 US claimed
US-8642685-B2 Liquid hardening OMG UK Technology, Ltd (GB) 2014-02-04 US claimed
US-20130041079-A1 LIQUID HARDENING OMG UK TECHNOLOGY LTD. (GB) 2013-02-14 US claimed
US-20230257500-A1 RADICALLY POLYMERIZABLE COMPOSITIONS BNY MELLON CORPORATE TRUSTEE SERVICES LIMITED, AS SECURITY AGENT (GB) 2023-08-17 US disclosed
US-11518834-B2 Radically polymerizable compositions Polynt Composites USA, Inc. (US) 2022-12-06 US disclosed
US-11193038-B2 Drier compositions for alkyd resins ALLNEX AUSTRIA GMBH (AT) 2021-12-07 US disclosed
EP-3906265-A1 RADICALLY POLYMERIZABLE COMPOSITIONS Polynt Composites USA Inc. (US) 2021-11-10 EP disclosed
EP-2760899-B1 COATING COMPOSITION AND USE THEREOF PPG EUROPE B V (NL) 2020-08-19 EP disclosed
WO-2020142632-A1 RADICALLY POLYMERIZABLE COMPOSITIONS Polynt Composites USA, Inc. (US) 2020-07-09 WO disclosed
US-20200207895-A1 RADICALLY POLYMERIZABLE COMPOSITIONS BNY MELLON CORPORATE TRUSTEE SERVICES LIMITED, AS SECURITY AGENT (GB) 2020-07-02 US disclosed
US-20190309185-A1 DRIER COMPOSITIONS FOR ALKYD RESINS ALLNEX AUSTRIA GMBH (AT) 2019-10-10 US disclosed
WO-2011157673-A1 ACCELERATOR SOLUTION AND PROCESS FOR CURING CURABLE RESINS AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2011-12-22 WO disclosed
US-20110277665-A1 LIQUID HARDENING Conopco, Inc. dba Unilever (US) 2011-11-17 US disclosed
US-8013044-B2 Liquid hardening CONOPCO, INC. (US) 2011-09-06 US disclosed
WO-2011083309-A1 CURING LIQUIDS UNILEVER PLC (GB) 2011-07-14 WO disclosed
EP-2343336-A1 Curing liquids Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2011-07-13 EP disclosed
EP-2038356-B1 LIQUID HARDENING UNILEVER PLC (GB) 2010-08-11 EP disclosed
US-20090253833-A1 Liquid Hardening OMG UK TECHNOLOGY LTD (GB) 2009-10-08 US disclosed
EP-2103735-A1 Catalytic bleaching of substrates Unilever PLC (GB) 2009-09-23 EP disclosed