SCHEMBL825216

SCHEMBL825216

CN(Cc1ccccn1)/C(Cc1ccccn1)=C(/N)Cc1ccccn1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.45
MAPT P10636 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
LIN28A Q9H9Z2 1/20 0.45
LMNA P02545 1/20 0.39
KCNA5 P22460 1/20 0.39
HRH1 P35367 1/20 0.39
KMT2A Q03164 1/20 0.38
KDM4E B2RXH2 2/20 0.38
TSHR P16473 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
POLB P06746 1/20 0.38
RAB9A P51151 2/20 0.37
NPC1 O15118 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CA2 P00918 1/20 0.37
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
NTRK1 P04629 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7890898 0.78 HRH1 (0.54) TDP1MAPTSMN1; SMN2LIN28ALMNA
SCHEMBL7890891 0.78 HRH1 (0.54) TDP1MAPTSMN1; SMN2LIN28ALMNA
SCHEMBL9259765 0.78 SMN1; SMN2 (0.50) TDP1MAPTSMN1; SMN2LIN28ALMNA
SCHEMBL7976764 0.78 SMN1; SMN2 (0.50) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL1332881 0.77 SMN1; SMN2 (0.41) TDP1MAPTSMN1; SMN2LIN28ALMNA
SCHEMBL825264 0.77 SMN1; SMN2 (0.41) TDP1MAPTSMN1; SMN2LIN28ALMNA
SCHEMBL427048 0.72 SMN1; SMN2 (0.52) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL6204342 0.72 KDM4E (0.52) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL7976763 0.71 SMN1; SMN2 (0.50) TDP1MAPTSMN1; SMN2LIN28AKCNA5
SCHEMBL427047 0.71 SMN1; SMN2 (0.50) TDP1MAPTSMN1; SMN2LIN28AKCNA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9593232-B2 Liquid hardening OMG UK TECHNOLOGY LTD. (GB) 2017-03-14 US claimed
US-9150705-B2 Curing liquids OMG ADDITIVES LIMITED (GB) 2015-10-06 US claimed
EP-2521750-B1 CURING LIQUIDS OMG UK TECHNOLOGY LTD (GB) 2014-07-02 EP claimed
US-20140155525-A1 LIQUID HARDENING OMG UK TECHNOLOGY LTD. (GB) 2014-06-05 US claimed
US-8642685-B2 Liquid hardening OMG UK Technology, Ltd (GB) 2014-02-04 US claimed
US-20130123452-A1 CURING LIQUIDS OMG ADDITIVES LIMITED (UK) 2013-05-16 US claimed
US-20130041079-A1 LIQUID HARDENING OMG UK TECHNOLOGY LTD. (GB) 2013-02-14 US claimed
EP-2521750-A1 CURING LIQUIDS OMG Additives Limited (GB) 2012-11-14 EP claimed
WO-2011083309-A1 CURING LIQUIDS UNILEVER PLC (GB) 2011-07-14 WO claimed
EP-2343336-A1 Curing liquids Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2011-07-13 EP claimed
EP-2038356-B1 LIQUID HARDENING UNILEVER PLC (GB) 2010-08-11 EP claimed
US-20090253833-A1 Liquid Hardening OMG UK TECHNOLOGY LTD (GB) 2009-10-08 US claimed
US-20230257500-A1 RADICALLY POLYMERIZABLE COMPOSITIONS BNY MELLON CORPORATE TRUSTEE SERVICES LIMITED, AS SECURITY AGENT (GB) 2023-08-17 US disclosed
US-11518834-B2 Radically polymerizable compositions Polynt Composites USA, Inc. (US) 2022-12-06 US disclosed
US-11193038-B2 Drier compositions for alkyd resins ALLNEX AUSTRIA GMBH (AT) 2021-12-07 US disclosed
EP-3906265-A1 RADICALLY POLYMERIZABLE COMPOSITIONS Polynt Composites USA Inc. (US) 2021-11-10 EP disclosed
EP-2343336-A1 Curing liquids Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2011-07-13 EP disclosed
EP-2038356-B1 LIQUID HARDENING UNILEVER PLC (GB) 2010-08-11 EP disclosed
US-20090253833-A1 Liquid Hardening OMG UK TECHNOLOGY LTD (GB) 2009-10-08 US disclosed
EP-2103735-A1 Catalytic bleaching of substrates Unilever PLC (GB) 2009-09-23 EP disclosed