Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8249287 | 0.85 | KDM4A (0.35) | KDM4ACA12CA1CA2CA9 | |
| SCHEMBL8255477 | 0.83 | FPR3 (0.36) | KDM4ACA12CA1CA2CA9 | |
| SCHEMBL8249310 | 0.83 | KDM4A (0.36) | KDM4ACA12CA1CA2CA9 | |
| SCHEMBL13594020 | 0.81 | CTSS (0.36) | KDM4APTPN11 | |
| SCHEMBL13185407 | 0.81 | KDM4A (0.37) | KDM4ACA12CA1CA2CA9 | |
| SCHEMBL8252983 | 0.80 | KDM4A (0.34) | KDM4ACA12CA1CA2CA9 | |
| SCHEMBL8245984 | 0.77 | KDM4A (0.34) | KDM4ACA12CA1CA2CA9 | |
| SCHEMBL13185408 | 0.75 | USP2 (0.38) | CA12CA1CA2CA9DRD2 | |
| SCHEMBL30602991 | 0.75 | ALDH1A1 (0.43) | KDM4ACA12CA1CA2CA9 | |
| SCHEMBL13594011 | 0.74 | CYP1A2 (0.34) | KDM4ACA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006128184-A2 | PYRIMIDINE OR TRIAZINE FUSED BICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS-PHARMACEUTICALS, INC. (US) | 2006-11-30 | — | — | WO | disclosed |