SCHEMBL825557

SCHEMBL825557

[Li]c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.53
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
HTR7 P34969 1/20 0.42
HTR2B P41595 1/20 0.42
MAOA P21397 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
BCHE P06276 2/20 0.39
CES1 P23141 1/20 0.39
DRD2 P14416 1/20 0.38
DRD4 P21917 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexane SCHEMBL8201767 0.88 PNMT (0.47) PNMTNPC1RAB9AHTR7HTR2B
Ether SCHEMBL6738747 0.86 PNMT (0.46) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL30103334 0.84 PNMT (0.63) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL524602 0.84 PNMT (0.63) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL9073162 0.83 PNMT (0.41) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL2877998 0.81 PNMT (0.61) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL22263591 0.79 PNMT (0.57) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL29459193 0.78 PNMT (0.53) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL4454303 0.78 PNMT (0.53) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL27885618 0.77 PNMT (0.57) PNMTNPC1RAB9AHTR7HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1572750-B1 CONTINUOUS PROCESS FOR THE PRODUCTION OF CONTROLLED ARCHITECTURE MATERIALS UNDER HIGH SOLIDS LOADING CONDITIONS 3M INNOVATIVE PROPERTIES CO (US) 2013-06-19 EP claimed
EP-0870780-B1 Initiator system comprising an heterocyclic ligand for the anionic (co)polymerisation of (meth)acrylic monomers and polymerisation process using it ATOFINA (FR) 2004-09-15 EP claimed
EP-1304319-A2 Metallocenes and processes therefor and therewith Phillips Petroleum Company (US) 2003-04-23 EP claimed
US-6355747-B1 FOR POLYMERIZATION OF PROPYLENE TO PRODUCE ISOTACTIC POLYPROPYLENE SOLVAY POLYOLEFINS EUROPE-BELGIUM (BE) 2002-03-12 US claimed
US-6262204-B1 AS POLYMERIZATION INITIATOR FOR POLYMERIZATION OF (METH)ACRYLIC MONOMERS AND OPTIONALLY ETHYLENICALLY UNSATURATED MONOMERS ATOFINA (FR) 2001-07-17 US claimed
US-20010003726-A1 INITIATION SYSTEM COMPRISING AN AMINO ALCOHOLATE LIGAND FOR ANIONIC COPOLYMERIZATION OF (METH)ACRYLIC MONOMERS AND PROCESS USING SAME ELF ATOCHEM S.A. (FR) 2001-06-14 US claimed
EP-1077215-A1 Asymmetric silicon-bridged metallocenes useful as catalysts in the polymerization of a-olefins, process for their preparation and use of said metallocenes for the polymerization of a-olefins SOLVAY POLYOLEFINS EUROPE - BELGIUM (Société Anonyme) (BE) 2001-02-21 EP claimed
US-6100416-A SUCH AS 1-(9-FLUORENYL)-2-(1-(2,4,7-TRIMETHYL)INDENYL)ETHANE ZIRCONIUM DICHLORIDE; SYNTHESIS FROM 1,2-DIBROMOETHANE, FLUORENYLLITHIUM, TRIMETHYLINDENYLLITHIUM, BUTYLLITHIUM AND TRANSITION METAL HALIDE; USE TO MAKE ISOTACTIC POLYPROPYLENE SOLVAY POLYOLEFINS EUROPE-BELGIUM (SOCIETE ANONYME) (BE) 2000-08-08 US claimed
US-6069207-A ANIONIC POLYMERIZATE OF AT LEAST TWO MONOMERS IN PRESENCE OF AT LEAST ONE ALKALI OR ALKALINE EARTH METAL, MONO- OR DIFUNCTIONAL INITIATOR AND LIGAND SELECTED FROM NONNITROGENOUS MACROCYCLIC COMPLEXANT OR ALKALI METAL ALCOHOLATE ELF ATOCHEM S.A. (FR) 2000-05-30 US claimed
EP-0962462-A2 Novel asymmetric ethylene-bridged metallocenes useful as catalysts in the polymerization of olefins and process for preparing said metallocenes SOLVAY POLYOLEFINS EUROPE - BELGIUM (Société Anonyme) (BE) 1999-12-08 EP claimed
US-5670592-A POLYMERIZATION WITH ORGANOLITHIUM COMPOUNDS, PYRIDINE AND ORGANOALUMINUM COMPOUNDS AS CATALYSTS ELF ATOCHEM S.A. (FR) 1997-09-23 US claimed
EP-0551221-B1 Process for the preparation of star or network multiblock polycondensates by coupling di- or multi-adhehydes, and polycondensate thus obtained ATOCHEM ELF SA (FR) 1997-06-04 EP claimed
US-5616752-A CYCLOPENTADIENYL-TYPE SILANE-CONTAINING POLYMERIZATION CATALYSTS PHILLIPS PETROLEUM COMPANY (US) 1997-04-01 US claimed
US-5561207-A USING COORDINATION CATALYST ELF ATOCHEM S.A. (FR) 1996-10-01 US claimed
EP-0686647-A1 Process for preparing methyl methacrylate with high level of syndiotactic triads ELF ATOCHEM S.A. (FR) 1995-12-13 EP claimed
EP-0668297-A1 Living statistic (meth)acrylat copolymers, copolymers prepared from these living copolymers, and process for preparing these copolymers by anionic copolymerisation ELF ATOCHEM S.A. (FR) 1995-08-23 EP claimed
US-5399636-A Bound to inorganic support, olefin polymerization catalysts PHILLIPS PETROLEUM COMPANY (US) 1995-03-21 US claimed
EP-0628566-A1 Metallocenes and processes therefor and therewith PHILLIPS PETROLEUM COMPANY (US) 1994-12-14 EP claimed
US-5346956-A Process for manufacturing multisequence star or network polycondensates by di- or multi-aldehyde coupling, and polycondensates obtained ELF ATOCHEM S.A. (FR) 1994-09-13 US claimed
EP-0551221-A1 Process for the preparation of star or network multiblock polycondensates by coupling di- or multi-adhehydes, and polycondensate thus obtained ELF ATOCHEM S.A. (FR) 1993-07-14 EP claimed