Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825557 | 0.86 | PNMT (0.53) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hexane SCHEMBL8201767 | 0.85 | PNMT (0.47) | PNMTNPC1RAB9AHTR7HTR2B | |
| Ether SCHEMBL9618978 | 0.81 | PNMT (0.46) | PNMTNPC1RAB9AHTR7HTR2B | |
| Fluorene SCHEMBL4847437 | 0.80 | MAOA (0.48) | PNMTNPC1RAB9AHTR2BGABRP | |
| SCHEMBL1275883 | 0.77 | PNMT (0.58) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL9073162 | 0.75 | PNMT (0.41) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL31192159 | 0.75 | PNMT (0.44) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL28066660 | 0.73 | PNMT (0.49) | PNMTNPC1RAB9AHTR2BGABRP | |
| SCHEMBL27879935 | 0.73 | PNMT (0.53) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL28989984 | 0.72 | PNMT (0.47) | PNMTNPC1RAB9AGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6693153-B2 | USING COORDINATION CATALYST | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2004-02-17 | — | — | US | disclosed |
| US-20030139544-A1 | Catalyst system for the polymerization of alkenes to polyolefins | ENERGY, UNITED STATES DEPARTMENT OF | 2003-07-24 | — | — | US | disclosed |
| US-6469188-B1 | CATALYST SYSTEMS PARTICULARLY USEFUL FOR THE POLYMERIZATION OF POLYPROPYLENE TO GIVE ELASTOMERIC POLYPROPYLENES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2002-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139544-A1 | Catalyst system for the polymerization of alkenes to polyolefins | MSH2, PMS2, SDC4 | PNMT 337/4885NPC1 4815/4885RAB9A 4853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.