Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825557 | 0.88 | PNMT (0.53) | PNMTNPC1RAB9AALDH1A1HTR7 | |
| Ether SCHEMBL6738747 | 0.85 | PNMT (0.46) | PNMTNPC1RAB9AALDH1A1HTR7 | |
| Hexane SCHEMBL8572947 | 0.80 | PNMT (0.47) | PNMTNPC1RAB9ASIGMAR1ALDH1A1 | |
| Fluorene SCHEMBL25291666 | 0.80 | MAOA (0.50) | PNMTNPC1RAB9ASIGMAR1ALDH1A1 | |
| SCHEMBL5823386 | 0.79 | PNMT (0.58) | PNMTNPC1RAB9AALDH1A1CYP1A2 | |
| Fluorene SCHEMBL27803639 | 0.78 | ALDH1A1 (0.50) | PNMTNPC1RAB9ASIGMAR1ALDH1A1 | |
| Fluorene SCHEMBL28135016 | 0.78 | ALDH1A1 (0.50) | PNMTNPC1RAB9ASIGMAR1ALDH1A1 | |
| SCHEMBL407782 | 0.78 | PNMT (0.57) | PNMTALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL28825898 | 0.78 | PNMT (0.57) | PNMTALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6672769 | 0.78 | PNMT (0.57) | PNMTALDH1A1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984989-A1 | METALLOCENE CATALYST COMPONENT FOR USE IN PRODUCING ISOTACTIC POLYOLEFINS | FINA RESEARCH S.A. (BE) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998054230-A1 | METALLOCENE CATALYST COMPONENT FOR USE IN PRODUCING ISOTACTIC POLYOLEFINS | FINA RESEARCH S.A. (BE) | 1998-12-03 | — | — | WO | disclosed |