Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084534 | 0.86 | ALDH1A1 (0.50) | HTR7ALDH1A1KDM4EMAOAPTGS1 | |
| SCHEMBL6982625 | 0.84 | TSHR (0.41) | TSHRHTR7LMNAMAPTNPC1 | |
| SCHEMBL7946808 | 0.81 | HTR7 (0.45) | HTR7ADRA1DADRA1AADRA1BLMNA | |
| SCHEMBL7113219 | 0.76 | LMNA (0.38) | LMNAMAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8256396 | 0.74 | HTR7 (0.58) | TSHRHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL7731144 | 0.72 | CCNE2 (0.56) | TSHRHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL3433353 | 0.72 | HTR7 (0.41) | TSHRHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL7126204 | 0.72 | HTR7 (0.50) | HTR7ADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL6726288 | 0.72 | HTR7 (0.39) | TSHRHTR7ADRA1DADRA1AADRA1B | |
| SCHEMBL6730951 | 0.72 | HTR7 (0.39) | TSHRHTR7ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1034168-A1 | SUBSTITUTED ARYLOXY ALKYL AMINO TRIAZINES | Bayer Aktiengesellschaft (DE) | 2000-09-13 | — | — | EP | disclosed |
| WO-1999021841-A1 | SUBSTITUTED ARYLOXY ALKYL AMINO TRIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-05-06 | — | — | WO | disclosed |