Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3547012 | 0.80 | GAA (0.36) | KMT2AMEN1GAAUSP2TSHR | |
| SCHEMBL13893217 | 0.79 | NOTUM (0.55) | KMT2AHTTPOLBSMN1; SMN2KDM4E | |
| SCHEMBL14612493 | 0.79 | ADRA2C (0.55) | KMT2APOLBMAPTLMNA | |
| SCHEMBL14330878 | 0.79 | GPR119 (0.36) | KMT2AMEN1GAAUSP2TSHR | |
| SCHEMBL14330895 | 0.78 | GAA (0.52) | KMT2AMEN1GAATSHRPKM | |
| SCHEMBL14095903 | 0.77 | CKS1B (0.47) | — | |
| SCHEMBL14471064 | 0.75 | ADRB1 (0.56) | TSHRALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL21261268 | 0.75 | SMN1; SMN2 (0.46) | KMT2AMEN1GAAUSP2TSHR | |
| SCHEMBL13798999 | 0.75 | PARP1 (0.35) | KMT2AGAATSHRALDH1A1HTT | |
| SCHEMBL3551745 | 0.75 | CHRNA7 (0.51) | GAASMN1; SMN2KDM4ETP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006097293-A2 | COMBINATION OF A STEROID SULFATASE INHIBITOR AND AN ASCOMYCIN | NOVARTIS AG (CH) | 2006-09-21 | — | — | WO | disclosed |