Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 12/20 | 0.46 |
| ▸ | ABL1 | P00519 | 4/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8258483 | 0.92 | IL2 (0.55) | IL2ABL1 | |
| SCHEMBL8259823 | 0.86 | IL2 (0.46) | IL2ABL1 | |
| SCHEMBL8256822 | 0.86 | IL2 (0.46) | IL2ABL1RIPK2 | |
| SCHEMBL8258543 | 0.84 | IL2 (0.50) | IL2ABL1 | |
| SCHEMBL8263029 | 0.82 | IL2 (0.44) | IL2ABL1 | |
| SCHEMBL8260057 | 0.82 | IL2 (0.46) | IL2ABL1RIPK2 | |
| SCHEMBL5555293 | 0.82 | IL2 (0.51) | IL2ABL1 | |
| SCHEMBL8252030 | 0.81 | IL2 (0.46) | IL2ABL1RIPK2 | |
| SCHEMBL5554369 | 0.81 | IL2 (0.51) | IL2ABL1 | |
| SCHEMBL8260246 | 0.81 | LMNA (0.39) | IL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006081391-A2 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2006-08-03 | — | — | WO | disclosed |