Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13872653 | 0.95 | ELANE (0.67) | ELANECYP2C9 | |
| SCHEMBL13872625 | 0.94 | ELANE (0.76) | ELANECYP2C9 | |
| SCHEMBL13872591 | 0.94 | ELANE (0.76) | ELANECYP2C9 | |
| SCHEMBL13359560 | 0.93 | ELANE (0.67) | ELANECYP2C9 | |
| SCHEMBL13872666 | 0.93 | ELANE (0.64) | ELANECYP2C9 | |
| SCHEMBL13872586 | 0.92 | ELANE (0.55) | ELANECYP2C9 | |
| SCHEMBL13872668 | 0.92 | ELANE (0.66) | ELANECYP2C9 | |
| SCHEMBL13872579 | 0.91 | ELANE (0.74) | ELANECYP2C9 | |
| SCHEMBL13359512 | 0.91 | ELANE (0.67) | ELANECYP2C9 | |
| SCHEMBL13872835 | 0.91 | ELANE (0.65) | ELANECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856059-B1 | MULTIMERS OF PYRIMIDINONE DERIVATIVES AND THEIR USE AS HUMAN NEUTROPHIL ELASTASE INHIBITORS | ARGENTA DISCOVERY LTD (GB) | 2010-05-19 | — | — | EP | disclosed |
| US-20090111795-A1 | Multimers of Heterocyclic Compounds and Their Use | ARGENTA DISCOVERY LIMITED (GB) | 2009-04-30 | — | — | US | disclosed |
| US-20090111795-A1 | Multimers of Heterocyclic Compounds and Their Use | ARGENTA DISCOVERY LIMITED (GB) | 2009-04-30 | — | — | US | disclosed |
| WO-2006082412-A2 | MULTIMERS OF PYRIMIDINONE DERIVATIVES AND THEIR USE AS HUMAN NEUTROPHIL ELASTASE INHIBITORS | ARGENTA DISCOVERY LIMITED (GB) | 2006-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111795-A1 | Multimers of Heterocyclic Compounds and Their Use | MRM1, ME2, SDHA | ELANE 293/4885CYP2C9 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.