Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 6/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2492871 | 0.89 | MAPT (0.47) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| SCHEMBL146408 | 0.87 | ADRA2A (0.52) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| Hydrochloric Acid SCHEMBL9161665 | 0.85 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| Ammonia Solution, Strong SCHEMBL11136136 | 0.85 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| SCHEMBL9322409 | 0.82 | LMNA (0.53) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| SCHEMBL7011411 | 0.81 | CYP3A4 (0.50) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| SCHEMBL9013552 | 0.81 | MAPT (0.54) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| SCHEMBL1800842 | 0.79 | MAPT (0.45) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| Oxirane SCHEMBL27491261 | 0.78 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| SCHEMBL11223017 | 0.77 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003478-A2 | DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY | VENTANA MEDICAL SYSTEMS, INC. (US) | 2012-01-05 | — | — | WO | disclosed |