Cyclohexylamine

Cyclohexylamine

SCHEMBL825877

C1CC1.CO[SiH](OC)OC.NC1CCCCC1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
MMP1 P03956 1/20 0.31
MMP8 P22894 1/20 0.31
ADRA1A P35348 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexylamine SCHEMBL28821598 1.00 THRB (0.32) THRBMEN1KMT2AMMP1MMP8
Cyclohexylamine SCHEMBL16192487 0.97 THRB (0.30) THRBMEN1KMT2AMMP1MMP8
SCHEMBL6895751 0.89
SCHEMBL3837099 0.78 ALDH1A1 (0.47) ALDH1A1
Cycloheptanamine SCHEMBL6866616 0.76 THRB (0.44) THRBMEN1KMT2AMMP1MMP8
Cyclohexylamine SCHEMBL1679773 0.76
Cyclooctanamine SCHEMBL6863778 0.76 THRB (0.44) THRBMEN1KMT2AMMP1MMP8
Cyclopropane SCHEMBL10622264 0.76
Cyclopropane SCHEMBL825539 0.76
Cyclooctanamine SCHEMBL3037563 0.76 THRB (0.44) THRBMEN1KMT2AMMP1MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106459362-B Silylated polyurethanes 亨茨曼国际有限公司 2020-10-13 CN claimed
US-10351656-B2 Silylated polyurethanes HUNTSMAN INTERNATIONAL LLC (US) 2019-07-16 US claimed
EP-3157970-B1 SILYLATED POLYURETHANES HUNTSMAN INT LLC (US) 2019-02-06 EP claimed
US-20170198084-A1 SILYLATED POLYURETHANES HUNTSMAN INTERNATIONAL LLC 2017-07-13 US claimed
EP-3157970-A1 SILYLATED POLYURETHANES Huntsman International LLC (US) 2017-04-26 EP claimed
EP-2957582-A1 Isocyanate-based prepolymers HUNTSMAN INTERNATIONAL LLC (US) 2015-12-23 EP claimed
WO-2015193146-A1 SILYLATED POLYURETHANES HUNTSMAN INTERNATIONAL LLC (US) 2015-12-23 WO claimed
US-20220220247-A1 Composition Comprising Silylated Polymer HUNTSMAN INTERNATIONAL LLC 2022-07-14 US disclosed
EP-3976707-A1 COMPOSITION COMPRISING SILYLATED POLYMER Huntsman International LLC (US) 2022-04-06 EP disclosed
CN-113966360-A Compositions comprising silylated polymers 亨茨曼国际有限公司 2022-01-21 CN disclosed
WO-2020239746-A1 COMPOSITION COMPRISING SILYLATED POLYMER HUNTSMAN INTERNATIONAL LLC (US) 2020-12-03 WO disclosed
CN-106459362-B Silylated polyurethanes 亨茨曼国际有限公司 2020-10-13 CN disclosed
US-10351656-B2 Silylated polyurethanes HUNTSMAN INTERNATIONAL LLC (US) 2019-07-16 US disclosed
EP-2957582-A1 Isocyanate-based prepolymers HUNTSMAN INTERNATIONAL LLC (US) 2015-12-23 EP disclosed
WO-2015193146-A1 SILYLATED POLYURETHANES HUNTSMAN INTERNATIONAL LLC (US) 2015-12-23 WO disclosed
WO-2014173638-A1 COMPOSITION COMPRISING SILYLATED POLYMERS HUNTSMAN INTERNATIONAL LLC (US) 2014-10-30 WO disclosed
EP-2796493-A1 Composition comprising silylated polymers and polyhedral oligomeric metallo silsesquioxane HUNTSMAN INTERNATIONAL LLC (US) 2014-10-29 EP disclosed
EP-2582737-A1 ALKOXYSILANE FUNCTIONALIZED ISOCYANATE BASED MATERIALS Huntsman International LLC (US) 2013-04-24 EP disclosed
US-20130079538-A1 ALKOXYSILANE FUNCTIONALIZED ISOCYANATE BASED MATERIALS Huntsman Internatioanl LLC (US) 2013-03-28 US disclosed
WO-2011161011-A1 ALKOXYSILANE FUNCTIONALIZED ISOCYANATE BASED MATERIALS HUNTSMAN INTERNATIONAL LLC (US) 2011-12-29 WO disclosed