Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8260532 | 0.83 | PLA2G2A (0.39) | ADORA3PKML3MBTL1LMNAALDH1A1 | |
| SCHEMBL13587794 | 0.81 | NR3C2 (0.49) | NR3C2HTTGAANPSR1MAPT | |
| SCHEMBL13587734 | 0.76 | NR3C2 (0.46) | NR3C2 | |
| SCHEMBL8261070 | 0.69 | NR3C2 (0.57) | NR3C2 | |
| SCHEMBL8258774 | 0.69 | ADORA2B (0.44) | NR3C2CACNA1DHTTADORA3GAA | |
| SCHEMBL8261135 | 0.69 | NPC1 (0.39) | CACNA1DGAAL3MBTL1LMNAALDH1A1 | |
| SCHEMBL8260834 | 0.67 | NR3C2 (0.58) | NR3C2 | |
| SCHEMBL8258517 | 0.67 | — | — | |
| SCHEMBL13587787 | 0.67 | NR3C2 (0.44) | NR3C2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8261162 | 0.67 | L3MBTL1 (0.40) | NR3C2CACNA1DGAAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006066011-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF STEROIDAL RECEPTORS AND CALCIUM CHANNEL ACTIVITIES | IRM LLC (BM) | 2006-06-22 | — | — | WO | disclosed |