Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 13/20 | 0.64 |
| ▸ | ACHE | P22303 | 13/20 | 0.64 |
| ▸ | BCHE | P06276 | 12/20 | 0.64 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885290 | 1.00 | BACE1 (0.64) | BACE1ACHEBCHEDRD2DRD4 | |
| SCHEMBL13761943 | 1.00 | BACE1 (0.64) | BACE1ACHEBCHEDRD2DRD4 | |
| SCHEMBL13761638 | 0.91 | ALDH1A1 (0.60) | BACE1ACHEBCHEALDH1A1 | |
| SCHEMBL3307906 | 0.91 | ACHE (0.62) | BACE1ACHEBCHEALDH1A1MEN1 | |
| SCHEMBL21569736 | 0.87 | ACHE (0.50) | BACE1ACHEBCHEALDH1A1 | |
| SCHEMBL12844707 | 0.87 | BACE1 (0.59) | BACE1ACHEBCHEDRD2DRD4 | |
| SCHEMBL242760 | 0.83 | ACHE (0.69) | BACE1ACHEBCHEDRD2DRD4 | |
| SCHEMBL724604 | 0.83 | ACHE (0.69) | BACE1ACHEBCHEDRD2DRD4 | |
| SCHEMBL242759 | 0.83 | ACHE (0.69) | BACE1ACHEBCHEDRD2DRD4 | |
| Bromide SCHEMBL2497824 | 0.81 | ACHE (0.68) | BACE1ACHEBCHEDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557110-B2 | MAPKAP-K2; inflammatory disease, autoimmune disease, destructive bone disorder, cancer and/or tumour growth; 5-[(trans-4-aminocyclohexyl)amino]-3-fluoro-6-methyl(pyrazolo[1,5-a]pyri- midin-7-yl)}(4-iodophenyl)amine | TEIJIN PHARMA LIMITED (JP) | 2009-07-07 | — | — | US | disclosed |
| US-20070275964-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER, INC. | 2007-11-29 | — | — | US | disclosed |
| US-7268133-B2 | Cannabinoid receptor ligands and uses thereof | PFIZER, INC. PATENT DEPARTMENT (US) | 2007-09-11 | — | — | US | disclosed |
| US-20040214837-A1 | Cannabinoid receptor ligands and uses thereof | PFIZER INC. | 2004-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214837-A1 | Cannabinoid receptor ligands and uses thereof | CNR1, CNR2, GPR18 | BACE1 1133/4885ACHE 1631/4885BCHE 1548/4885 |
| US-20070275964-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | CNR1, CNR2, GPR18 | BACE1 1289/4885ACHE 1667/4885BCHE 1446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.