Aniline

Aniline

SCHEMBL825918

C.CO[SiH](OC)OC.Nc1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.55
MAOA P21397 6/20 0.41
TDP1 Q9NUW8 5/20 0.40
CYP3A4 P08684 5/20 0.40
TAAR1 Q96RJ0 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MAPK1 P28482 2/20 0.39
ALDH1A1 P00352 6/20 0.38
MAOB P27338 5/20 0.37
CA4 P22748 1/20 0.36
MAPT P10636 6/20 0.36
L3MBTL1 Q9Y468 4/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
HTT P42858 2/20 0.36
RAB9A P51151 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP2D6 P10635 1/20 0.36
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aniline SCHEMBL4259459 0.97 TSHR (0.58) TSHRMAOATDP1CYP3A4TAAR1
Aniline SCHEMBL28307357 0.95 TSHR (0.55) TSHRMAOATDP1CYP3A4TAAR1
Aniline SCHEMBL223573 0.91 TSHR (0.50) TSHRMAOATDP1CYP3A4TAAR1
Aniline SCHEMBL28119117 0.81 TSHR (0.73) TSHRMAOATDP1CYP3A4TAAR1
Aniline SCHEMBL1702729 0.78
Aniline SCHEMBL9007751 0.78 TSHR (0.92) TSHRMAOATDP1CYP3A4TAAR1
Biphenyl SCHEMBL1048244 0.76 ALDH1A1 (0.53) TSHRTDP1CYP3A4TAAR1HSD17B10
Aniline SCHEMBL3890089 0.75 TSHR (0.73) TSHRMAOATDP1CYP3A4TAAR1
Aniline SCHEMBL14802038 0.75 TSHR (0.48) TSHRMAOATDP1CYP3A4TAAR1
Aniline SCHEMBL11818606 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106459362-B Silylated polyurethanes 亨茨曼国际有限公司 2020-10-13 CN claimed
US-10351656-B2 Silylated polyurethanes HUNTSMAN INTERNATIONAL LLC (US) 2019-07-16 US claimed
EP-3157970-B1 SILYLATED POLYURETHANES HUNTSMAN INT LLC (US) 2019-02-06 EP claimed
US-20170198084-A1 SILYLATED POLYURETHANES HUNTSMAN INTERNATIONAL LLC 2017-07-13 US claimed
EP-3157970-A1 SILYLATED POLYURETHANES Huntsman International LLC (US) 2017-04-26 EP claimed
EP-2957582-A1 Isocyanate-based prepolymers HUNTSMAN INTERNATIONAL LLC (US) 2015-12-23 EP claimed
WO-2015193146-A1 SILYLATED POLYURETHANES HUNTSMAN INTERNATIONAL LLC (US) 2015-12-23 WO claimed
US-20220220247-A1 Composition Comprising Silylated Polymer HUNTSMAN INTERNATIONAL LLC 2022-07-14 US disclosed
CN-113966360-A Compositions comprising silylated polymers 亨茨曼国际有限公司 2022-01-21 CN disclosed
WO-2020239746-A1 COMPOSITION COMPRISING SILYLATED POLYMER HUNTSMAN INTERNATIONAL LLC (US) 2020-12-03 WO disclosed
CN-106459362-B Silylated polyurethanes 亨茨曼国际有限公司 2020-10-13 CN disclosed
CN-110997314-B Composite material of metal and resin 株式会社新技术研究所 2020-10-09 CN disclosed
US-10351656-B2 Silylated polyurethanes HUNTSMAN INTERNATIONAL LLC (US) 2019-07-16 US disclosed
US-20160046793-A1 Composition Comprising Silylated Polymers HUNTSMAN INTERNATIONAL LLC 2016-02-18 US disclosed
EP-2957582-A1 Isocyanate-based prepolymers HUNTSMAN INTERNATIONAL LLC (US) 2015-12-23 EP disclosed
WO-2014173638-A1 COMPOSITION COMPRISING SILYLATED POLYMERS HUNTSMAN INTERNATIONAL LLC (US) 2014-10-30 WO disclosed
EP-2796493-A1 Composition comprising silylated polymers and polyhedral oligomeric metallo silsesquioxane HUNTSMAN INTERNATIONAL LLC (US) 2014-10-29 EP disclosed
EP-2582737-A1 ALKOXYSILANE FUNCTIONALIZED ISOCYANATE BASED MATERIALS Huntsman International LLC (US) 2013-04-24 EP disclosed
US-20130079538-A1 ALKOXYSILANE FUNCTIONALIZED ISOCYANATE BASED MATERIALS Huntsman Internatioanl LLC (US) 2013-03-28 US disclosed
WO-2011161011-A1 ALKOXYSILANE FUNCTIONALIZED ISOCYANATE BASED MATERIALS HUNTSMAN INTERNATIONAL LLC (US) 2011-12-29 WO disclosed