Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1201772 | 0.78 | RAB9A (0.45) | MAPTLMNASMN1; SMN2TSHRABL1 | |
| SCHEMBL1202202 | 0.66 | HPGDS (0.45) | MAPTLMNASMN1; SMN2TSHRABCB1 | |
| SCHEMBL29840564 | 0.66 | LCK (0.56) | KDM4EMAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL214090 | 0.66 | LCK (0.56) | KDM4EMAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL1202608 | 0.65 | HDAC3 (0.41) | KDM4EMAPK1MAPK10ABCB1ABCG2 | |
| Hydrochloric Acid SCHEMBL27800514 | 0.65 | LCK (0.55) | KDM4EMAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL3517826 | 0.64 | DHODH (0.45) | KDM4EALDH1A1LMNASMN1; SMN2GABRA1 | |
| SCHEMBL1201846 | 0.62 | MAOB (0.43) | MAPTSMN1; SMN2TSHRABCB1ABCG2 | |
| SCHEMBL1203117 | 0.60 | MAOB (0.51) | MAPTLMNASMN1; SMN2TSHRDRD2 | |
| SCHEMBL3519633 | 0.60 | MEN1 (0.47) | KDM4EMAPTALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006099379-A2 | BENZAZOLE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE AS B-SECRETASE INHIBITORS | TRANSTECH PHARMA, INC. (US) | 2006-09-21 | — | — | WO | disclosed |