Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5809271 | 0.84 | HDAC1 (0.71) | HDAC1NPC1MAPTRAB9APOLB | |
| SCHEMBL8258697 | 0.83 | HDAC1 (0.63) | HDAC1 | |
| SCHEMBL8257248 | 0.80 | HDAC1 (0.60) | HDAC1L3MBTL1 | |
| SCHEMBL8260320 | 0.78 | HDAC1 (0.67) | HDAC1NPC1MAPTRAB9A | |
| SCHEMBL5805572 | 0.74 | HDAC1 (0.71) | HDAC1RAB9A | |
| SCHEMBL5808017 | 0.73 | HDAC1 (0.62) | HDAC1NPC1MAPTRAB9APOLB | |
| SCHEMBL8257257 | 0.72 | HDAC1 (0.51) | HDAC1MAPT | |
| SCHEMBL1893680 | 0.72 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL5805563 | 0.72 | HDAC1 (0.73) | HDAC1 | |
| SCHEMBL8291158 | 0.72 | HDAC1 (0.69) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006101454-A1 | BENZOTHIOPHENE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2006-09-28 | — | — | WO | disclosed |