Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8260320 | 0.90 | HDAC1 (0.67) | HDAC1MAPTRAB9ANPC1 | |
| SCHEMBL5805563 | 0.85 | HDAC1 (0.73) | HDAC1 | |
| SCHEMBL8260306 | 0.84 | HDAC1 (0.55) | HDAC1MAPTRAB9ANPC1POLB | |
| SCHEMBL5808017 | 0.84 | HDAC1 (0.62) | HDAC1MAPTRAB9ANPC1KDM4E | |
| SCHEMBL1893680 | 0.83 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL5809353 | 0.82 | HDAC1 (0.54) | HDAC1MAPTKDM4E | |
| SCHEMBL1885021 | 0.81 | HDAC1 (0.83) | HDAC1MAPT | |
| SCHEMBL1886609 | 0.80 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL8258701 | 0.79 | HDAC1 (0.75) | HDAC1RAB9ANPC1POLB | |
| SCHEMBL6508547 | 0.78 | HDAC1 (0.76) | HDAC1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006101454-A1 | BENZOTHIOPHENE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS | S*BIO PTE LTD (SG) | 2006-09-28 | — | — | WO | claimed |