SCHEMBL8260696

SCHEMBL8260696

CC(C)(C)N1CCN(S(=O)(=O)CC(F)(F)F)CC1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.35
ADAMTS4 O75173 1/20 0.33
MMP13 P45452 1/20 0.33
MMP14 P50281 1/20 0.33
POLB P06746 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
LIPE Q05469 1/20 0.31
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL84444 0.81 POLB (0.41) POLBNPSR1L3MBTL1HSD17B10
SCHEMBL14388360 0.77 KMT2A (0.43) EPHX2POLBNPSR1L3MBTL1HSD17B10
SCHEMBL22550134 0.77 LMNA (0.41) EPHX2POLBNPSR1L3MBTL1
SCHEMBL16072938 0.74 GAA (0.38) POLBNPSR1L3MBTL1HSD17B10
SCHEMBL12227427 0.74 POLB (0.30) POLBNPSR1L3MBTL1
SCHEMBL22860158 0.74 EPHX2 (0.41) EPHX2LIPE
SCHEMBL8263009 0.73 KDM4E (0.46) EPHX2POLBL3MBTL1
SCHEMBL8713877 0.72 CA12 (0.48) EPHX2POLBL3MBTL1
SCHEMBL2246611 0.72 KDM4E (0.42) EPHX2
Hydrochloric Acid SCHEMBL2593006 0.71 KDM4E (0.41) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070275964-A1 CANNABINOID RECEPTOR LIGANDS AND USES THEREOF PFIZER, INC. 2007-11-29 US disclosed
US-7268133-B2 Cannabinoid receptor ligands and uses thereof PFIZER, INC. PATENT DEPARTMENT (US) 2007-09-11 US disclosed
US-20040214837-A1 Cannabinoid receptor ligands and uses thereof PFIZER INC. 2004-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040214837-A1 Cannabinoid receptor ligands and uses thereof CNR1, CNR2, GPR18 EPHX2 1309/4885ADAMTS4 4387/4885MMP13 4431/4885
US-20070275964-A1 CANNABINOID RECEPTOR LIGANDS AND USES THEREOF CNR1, CNR2, GPR18 EPHX2 1248/4885ADAMTS4 4378/4885MMP13 4443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.