Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 12/20 | 0.48 |
| ▸ | ACHE | P22303 | 9/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282166 | 0.85 | ACHE (0.53) | BCHEACHEDRD2 | |
| SCHEMBL5282667 | 0.84 | BCHE (0.55) | BCHEACHEDRD2 | |
| SCHEMBL5291489 | 0.84 | BCHE (0.52) | BCHEACHEDRD2 | |
| SCHEMBL5278655 | 0.84 | BCHE (0.59) | BCHEACHEDRD2 | |
| SCHEMBL5289480 | 0.84 | BCHE (0.56) | BCHEACHEDRD2 | |
| SCHEMBL5279913 | 0.82 | BCHE (0.60) | BCHEACHEDRD2 | |
| SCHEMBL5280283 | 0.79 | KMT2A (0.51) | BCHEACHE | |
| SCHEMBL5280288 | 0.79 | KMT2A (0.51) | BCHEACHE | |
| SCHEMBL5280165 | 0.79 | BCHE (0.49) | BCHEACHE | |
| SCHEMBL5282971 | 0.79 | BCHE (0.47) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |