Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8259138 | 0.86 | GAA (0.40) | GAAGFERCDC7CDK9HCRTR1 | |
| SCHEMBL8259193 | 0.83 | MGLL (0.39) | GAAGFERALDH1A1HPGDMAPT | |
| SCHEMBL8260270 | 0.76 | GAA (0.38) | GAAGFERALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2563082 | 0.74 | ALDH1A1 (0.51) | GAACDC7CDK9NPC1RAB9A | |
| SCHEMBL2559890 | 0.74 | NOTUM (0.56) | GAAHPGDKDM4EHSD17B10 | |
| SCHEMBL13176039 | 0.74 | CCR2 (0.41) | HCRTR1HCRTR2NPC1RAB9AALDH1A1 | |
| SCHEMBL2559047 | 0.73 | NOTUM (0.49) | GAACDC7CDK9EPHX2NPC1 | |
| SCHEMBL11277428 | 0.72 | CSNK2A1 (0.44) | GAAHCRTR1HCRTR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL13175832 | 0.71 | CCR2 (0.41) | RAB9AALDH1A1HPGDCCR1CCR2 | |
| SCHEMBL27376861 | 0.70 | CDC7 (0.44) | GAAGFERCDC7CDK9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006097293-A2 | COMBINATION OF A STEROID SULFATASE INHIBITOR AND AN ASCOMYCIN | NOVARTIS AG (CH) | 2006-09-21 | — | — | WO | disclosed |