Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602613 | 0.82 | OPRL1 (0.67) | CHRM4OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL4602609 | 0.82 | OPRL1 (0.67) | CHRM4OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL7974951 | 0.80 | CHRM4 (0.46) | CHRM4OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL6623585 | 0.80 | CHRM4 (0.46) | CHRM4OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL8186450 | 0.79 | NPC1 (0.56) | OPRL1NPC1RAB9AMMP9ADAM17 | |
| SCHEMBL8186451 | 0.79 | NPC1 (0.56) | OPRL1NPC1RAB9AMMP9ADAM17 | |
| SCHEMBL8195224 | 0.78 | HRH3 (0.54) | OPRM1OPRD1OPRK1NPC1RAB9A | |
| SCHEMBL8195157 | 0.78 | HRH3 (0.54) | OPRM1OPRD1OPRK1NPC1RAB9A | |
| SCHEMBL6625512 | 0.75 | CHRM4 (0.54) | CHRM4NPC1RAB9AALOX5MAPK1 | |
| SCHEMBL4602232 | 0.75 | CHRM4 (0.54) | CHRM4NPC1RAB9AALOX5MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000063173-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED PIPERIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-10-26 | — | — | WO | disclosed |