Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | DNM2 | P50570 | 4/20 | 0.39 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8263899 | 0.92 | CNR1 (0.46) | P2RX7CNR2POLBTERTDNM2 | |
| SCHEMBL27854488 | 0.86 | DNM2 (0.46) | CNR2DNM2CDC25A | |
| SCHEMBL1072521 | 0.84 | DNM2 (0.53) | CNR2DNM2CDC25A | |
| SCHEMBL1518736 | 0.83 | CNR2 (0.47) | CNR2MCHR1HDAC10HDAC6 | |
| SCHEMBL8264949 | 0.82 | ICMT (0.51) | CNR2TERTKMT2ACDC25AHDAC10 | |
| SCHEMBL16977262 | 0.82 | DNM2 (0.46) | CNR2TERTDNM2KMT2AHTR6 | |
| SCHEMBL1074732 | 0.81 | MAPK1 (0.47) | CNR2POLBTERTLMNAKMT2A | |
| SCHEMBL8264342 | 0.81 | KMT2A (0.52) | KMT2A | |
| SCHEMBL1518558 | 0.81 | CNR2 (0.48) | CNR2HRH1HRH4TERTDNM2 | |
| SCHEMBL13490856 | 0.81 | HRH2 (0.46) | DNM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006074924-A1 | 3,4,(5)-SUBSTITUTED TETRAHVDROPYRIDINES | NOVARTIS AG (CH) | 2006-07-20 | — | — | WO | disclosed |