Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10183497 | 0.83 | LMNA (0.58) | KMT2AALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL8264846 | 0.82 | GAA (0.44) | KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1518291 | 0.81 | HTR2C (0.54) | KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL8264241 | 0.81 | P2RX7 (0.46) | KMT2A | |
| SCHEMBL1518225 | 0.81 | PDE4B (0.42) | KMT2AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL30979650 | 0.81 | ALDH1A1 (0.55) | KMT2AALDH1A1TBXAS1STAT3S1PR2 | |
| SCHEMBL8264949 | 0.80 | ICMT (0.51) | KMT2AALDH1A1KDM4EMAPTRXFP1 | |
| SCHEMBL1074732 | 0.79 | MAPK1 (0.47) | KMT2AALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8263899 | 0.79 | CNR1 (0.46) | — | |
| SCHEMBL27854488 | 0.78 | DNM2 (0.46) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006074924-A1 | 3,4,(5)-SUBSTITUTED TETRAHVDROPYRIDINES | NOVARTIS AG (CH) | 2006-07-20 | — | — | WO | disclosed |