Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 7/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MTTP | P55157 | 2/20 | 0.37 |
| ▸ | CBLB | Q13191 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KLRK1 | P26718 | 1/20 | 0.36 |
| ▸ | MICA | Q29983 | 1/20 | 0.36 |
| ▸ | RAET1L | Q5VY80 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3238424 | 0.95 | CTSS (0.51) | CTSSSLC6A9USP2NR1H4ALDH1A1 | |
| SCHEMBL3238677 | 0.82 | SLC6A9 (0.62) | CTSSSLC6A9 | |
| SCHEMBL3234846 | 0.82 | SLC6A9 (0.61) | CTSSSLC6A9 | |
| SCHEMBL3233194 | 0.82 | CNR1 (0.40) | USP2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3240772 | 0.81 | SLC6A9 (0.45) | SLC6A9MEN1KMT2A | |
| SCHEMBL3238330 | 0.80 | KDM4E (0.49) | ALDH1A1HPGDTP53 | |
| SCHEMBL3243539 | 0.80 | MTTP (0.40) | SLC6A9MTTPKLRK1MICARAET1L | |
| SCHEMBL3238315 | 0.79 | ALDH1A1 (0.41) | USP2ALDH1A1HPGDMTTPMEN1 | |
| SCHEMBL3240602 | 0.79 | SLC6A9 (0.41) | SLC6A9USP2ALDH1A1HPGDMEN1 | |
| SCHEMBL8266491 | 0.79 | SLC6A9 (0.37) | SLC6A9ALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006067423-A1 | GLYCINE TRANSPORT INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-06-29 | — | — | WO | disclosed |