Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12958255 | 0.92 | DRD2 (0.48) | DRD2DRD4L3MBTL1TDP1DRD3 | |
| SCHEMBL30335968 | 0.91 | ALDH1A1 (0.57) | ALDH1A1RECQLDRD2DRD4L3MBTL1 | |
| SCHEMBL516564 | 0.91 | ALDH1A1 (0.57) | ALDH1A1RECQLDRD2DRD4L3MBTL1 | |
| SCHEMBL3715239 | 0.89 | ALDH1A1 (0.64) | ALDH1A1RECQLFFAR4 | |
| SCHEMBL4323479 | 0.88 | FFAR4 (0.57) | ALDH1A1RECQLDRD2DRD4DRD3 | |
| SCHEMBL8264152 | 0.88 | FFAR4 (0.50) | ALDH1A1RECQLDRD2DRD4L3MBTL1 | |
| SCHEMBL4320104 | 0.83 | ALDH1A1 (0.69) | ALDH1A1RECQLFFAR4 | |
| SCHEMBL515982 | 0.81 | DRD2 (0.58) | DRD2DRD4L3MBTL1TDP1DRD3 | |
| SCHEMBL12225772 | 0.81 | RXRA (0.57) | ALDH1A1L3MBTL1TDP1SMN1; SMN2KDM4E | |
| SCHEMBL18655582 | 0.81 | TSHR (0.59) | DRD2DRD4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833816-B1 | SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS | NOVARTIS AG (CH) | 2009-11-11 | — | — | EP | disclosed |
| WO-2006069788-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2006-07-06 | — | — | WO | disclosed |