Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13458590 | 0.91 | KMT2A (0.67) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL8266366 | 0.90 | SMN1; SMN2 (0.74) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL15333875 | 0.80 | RAB9A (0.64) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL14885455 | 0.78 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL1433698 | 0.77 | RAB9A (0.81) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL7606595 | 0.76 | KMT2A (0.70) | RAB9AKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL8265550 | 0.76 | SMN1; SMN2 (0.54) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL29952545 | 0.76 | ALDH1A1 (0.60) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL13627123 | 0.76 | RAB9A (0.59) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL19002729 | 0.76 | RAB9A (0.69) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177518-A1 | Organic compounds | Novartis AG (CH) | 2010-04-21 | — | — | EP | disclosed |
| WO-2006069788-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2006-07-06 | — | — | WO | disclosed |