Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.46 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.46 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19658451 | 0.81 | SMN1; SMN2 (0.54) | TPSAB1TPSD1TPSG1HTTSMN1; SMN2 | |
| SCHEMBL13558785 | 0.81 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1HTTSMN1; SMN2 | |
| SCHEMBL9144556 | 0.79 | HTT (0.51) | TPSAB1TPSD1TPSG1HTTSMN1; SMN2 | |
| SCHEMBL19652100 | 0.79 | SMN1; SMN2 (0.51) | TPSAB1TPSD1TPSG1HTTSMN1; SMN2 | |
| SCHEMBL19658635 | 0.78 | BCHE (0.49) | TPSAB1TPSD1TPSG1HTTSMN1; SMN2 | |
| SCHEMBL13597265 | 0.78 | SMN1; SMN2 (0.64) | HTTSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL8764844 | 0.77 | HTT (0.60) | TPSAB1TPSD1TPSG1HTTSMN1; SMN2 | |
| SCHEMBL3652558 | 0.76 | SMN1; SMN2 (0.61) | TPSAB1TPSD1TPSG1HTTSMN1; SMN2 | |
| SCHEMBL14794935 | 0.75 | SMN1; SMN2 (0.63) | HTTSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL12889378 | 0.75 | SMN1; SMN2 (0.63) | HTTSMN1; SMN2NPC1RAB9ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006065277-A2 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS | SCHERING CORPORATION (US) | 2006-06-22 | — | — | WO | disclosed |