Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 8/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7525422 | 0.97 | GAA (0.39) | GAAHPGDCNR1BRD4ATAD2 | |
| SCHEMBL7530815 | 0.88 | GAA (0.51) | GAAHPGDCNR1L3MBTL1KMT2A | |
| SCHEMBL7530986 | 0.88 | MEN1 (0.43) | GAAHPGDKCNH2KMT2AMMP12 | |
| SCHEMBL7523514 | 0.85 | ALDH1A1 (0.37) | GAAHPGDL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL7531137 | 0.85 | TRPV4 (0.39) | GAAHPGDL3MBTL1KMT2AMEN1 | |
| SCHEMBL7524858 | 0.83 | HSD11B1 (0.43) | GAAHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL7527062 | 0.83 | SLC13A5 (0.38) | GAAHPGDCNR1L3MBTL1KMT2A | |
| SCHEMBL7531033 | 0.82 | KMT2A (0.46) | GAABRD4ATAD2KMT2AMEN1 | |
| SCHEMBL7523271 | 0.81 | ALDH1A1 (0.48) | GAAHPGDL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL7525178 | 0.81 | ALDH1A1 (0.36) | GAAHPGDKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006065277-A2 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS | SCHERING CORPORATION (US) | 2006-06-22 | — | — | WO | disclosed |