Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.59 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13203130 | 0.87 | KDM4E (0.53) | HDAC6KDM4EMAPTHIF1ASLC22A6 | |
| SCHEMBL13009911 | 0.85 | HDAC6 (0.68) | HDAC6HDAC3NCOR2LOXL2MCHR1 | |
| SCHEMBL19634406 | 0.84 | KDM4E (0.68) | HDAC6HDAC3NCOR2LOXL2MCHR1 | |
| SCHEMBL19634418 | 0.84 | HDAC3 (0.61) | HDAC6HDAC3NCOR2LOXL2MCHR1 | |
| SCHEMBL21133441 | 0.83 | TAAR1 (0.47) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL8269151 | 0.83 | HDAC3 (0.56) | HDAC6HDAC3NCOR2LOXL2MCHR1 | |
| SCHEMBL5855594 | 0.82 | HDAC1 (0.45) | HDAC6KDM4EMAPTHIF1ASLC22A6 | |
| SCHEMBL13113151 | 0.81 | MAPT (0.70) | HDAC6HDAC3KDM4EMAPTHIF1A | |
| SCHEMBL13461011 | 0.81 | HDAC3 (0.63) | HDAC6HDAC3NCOR2LOXL2MCHR1 | |
| SCHEMBL19634398 | 0.81 | HDAC3 (0.54) | HDAC6HDAC3NCOR2LOXL2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014763-A1 | beta-sheet mimetics and composition and methods relating thereto | MYRIAD PHARMACEUTICALS, INC. (US) | 2004-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014763-A1 | beta-sheet mimetics and composition and methods relating thereto | TPSAB1, TPSB2, TPSD1 | HDAC6 2054/4885HDAC3 3559/4885NCOR2 4819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.