Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8269125 | 0.90 | HDAC3 (0.53) | HDAC3HDAC6NCOR2MCHR1LOXL2 | |
| SCHEMBL8269305 | 0.89 | MAPK1 (0.55) | HDAC3HDAC6NCOR2MCHR1ALDH1A1 | |
| SCHEMBL8269321 | 0.88 | MAPK1 (0.58) | HDAC3HDAC6NCOR2MCHR1CA2 | |
| SCHEMBL2650797 | 0.85 | CA1 (0.62) | HDAC3HDAC6NCOR2MCHR1LOXL2 | |
| SCHEMBL8269147 | 0.83 | HDAC6 (0.59) | HDAC3HDAC6NCOR2MCHR1LOXL2 | |
| SCHEMBL13113134 | 0.83 | LMNA (0.59) | HDAC3HDAC6CYP1A2TSHRNFKB1 | |
| SCHEMBL23254636 | 0.82 | CYP1A2 (0.68) | HDAC3HDAC6NCOR2MCHR1LOXL2 | |
| SCHEMBL13009911 | 0.82 | HDAC6 (0.68) | HDAC3HDAC6NCOR2MCHR1LOXL2 | |
| Hydrochloric Acid SCHEMBL6442968 | 0.81 | KMT2A (0.59) | HDAC3HDAC6NCOR2MCHR1LOXL2 | |
| SCHEMBL24386110 | 0.81 | HDAC6 (0.58) | HDAC3HDAC6NCOR2MCHR1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014763-A1 | beta-sheet mimetics and composition and methods relating thereto | MYRIAD PHARMACEUTICALS, INC. (US) | 2004-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014763-A1 | beta-sheet mimetics and composition and methods relating thereto | TPSAB1, TPSB2, TPSD1 | HDAC3 3559/4885HDAC6 2054/4885NCOR2 4819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.