Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | MGMT | P16455 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL827065 | 0.94 | — | — | |
| SCHEMBL826790 | 0.81 | ALDH1A1 (0.44) | ALDH1A1ALOX15TAAR1USP2NPSR1 | |
| SCHEMBL27451850 | 0.80 | CDK1 (0.35) | ALDH1A1ALOX15TAAR1USP2NPSR1 | |
| SCHEMBL28814389 | 0.78 | CXCR3 (0.36) | ALDH1A1ALOX15TAAR1USP2NPSR1 | |
| SCHEMBL826560 | 0.78 | ALDH1A1 (0.41) | ALDH1A1ALOX15TAAR1USP2NPSR1 | |
| SCHEMBL9414387 | 0.76 | ALDH1A1 (0.40) | ALDH1A1ALOX15TAAR1USP2NPSR1 | |
| SCHEMBL28297965 | 0.74 | ALDH1A1 (0.38) | ALDH1A1ALOX15TAAR1USP2NPSR1 | |
| SCHEMBL10881322 | 0.74 | CXCR3 (0.41) | ALDH1A1ALOX15TAAR1USP2NPSR1 | |
| SCHEMBL10881311 | 0.74 | CXCR3 (0.41) | ALDH1A1ALOX15TAAR1USP2NPSR1 | |
| SCHEMBL10881315 | 0.74 | CXCR3 (0.41) | ALDH1A1ALOX15TAAR1USP2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484523-B | Preparation method of optically pure trans-2- (diphenylphosphino) -1-cyclohexanecarboxylic acid | 南京工业大学 | 2022-07-08 | — | — | CN | claimed |
| CN-111484522-B | Preparation method of optically pure cis-2- (diphenylphosphino) -1-cyclohexanecarboxylic acid | 南京工业大学 | 2022-07-08 | — | — | CN | claimed |
| CN-111484523-A | Preparation method of optically pure trans-2- (diphenylphosphino) -1-cyclohexanecarboxylic acid | 南京工业大学 | 2020-08-04 | — | — | CN | claimed |
| CN-111484522-A | Preparation method of optically pure cis-2- (diphenylphosphino) -1-cyclohexanecarboxylic acid | 南京工业大学 | 2020-08-04 | — | — | CN | claimed |
| CN-104284884-B | Fluoro-substituted (3R,4R,5S) -5-guanidino-4-acetamido-3- (pentan-3-yloxy) cyclohexene-1-carboxylic acids, esters thereof and uses thereof | 阿斯阿维有限责任公司 | 2016-07-13 | — | — | CN | claimed |
| US-5045108-A | Herbicidal and plant growth-regulating N-aryl-pyrrol-L-one and isoindol-2-one compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | claimed |
| CN-116676290-A | Esterase GsEst mutant, engineering bacterium and application thereof in preparation of (S) -3-cyclohexene-1-formic acid | 浙江工业大学 | 2023-09-01 | — | — | CN | disclosed |
| CN-116376872-A | Recombinant esterase mutant, gene, engineering bacterium and application thereof | 浙江工业大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-116355876-A | Recombinant esterase mutant, engineering bacterium and application thereof in synthesis of (S) -3-cyclohexene-1-formic acid | 浙江工业大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-111484522-B | Preparation method of optically pure cis-2- (diphenylphosphino) -1-cyclohexanecarboxylic acid | 南京工业大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-111484523-B | Preparation method of optically pure trans-2- (diphenylphosphino) -1-cyclohexanecarboxylic acid | 南京工业大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-111484523-B | Preparation method of optically pure trans-2- (diphenylphosphino) -1-cyclohexanecarboxylic acid | 南京工业大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-111484522-B | Preparation method of optically pure cis-2- (diphenylphosphino) -1-cyclohexanecarboxylic acid | 南京工业大学 | 2022-07-08 | — | — | CN | disclosed |
| US-20090163488-A1 | FUSED HETEROCYCLE DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-25 | — | — | US | disclosed |
| US-20090137595-A1 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-2049541-A2 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008150015-A1 | HETEROBICYCLIC COMPOUNDS AS KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-11 | — | — | WO | disclosed |
| WO-2008016192-A2 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-02-07 | — | — | WO | disclosed |
| US-5045108-A | Herbicidal and plant growth-regulating N-aryl-pyrrol-L-one and isoindol-2-one compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | disclosed |
| EP-0403891-A1 | N-Aryl-nitrogen-heterocyclic compounds | BAYER AG (DE) | 1990-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137595-A1 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | KDR, FLT1, FLT4 | ALDH1A1 182/4885ALOX15 2826/4885TAAR1 3196/4885 |
| US-20090163488-A1 | FUSED HETEROCYCLE DERIVATIVES AND USE THEREOF | NOX3, NOX5, ZYX | ALDH1A1 2812/4885ALOX15 2802/4885TAAR1 890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.