Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 16/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8272192 | 0.91 | FDFT1 (0.40) | FDFT1ESR1PSEN1PSEN2APH1B | |
| SCHEMBL8272847 | 0.88 | FDFT1 (0.41) | FDFT1 | |
| SCHEMBL8272193 | 0.85 | FDFT1 (0.47) | FDFT1 | |
| SCHEMBL8275043 | 0.82 | FDFT1 (0.36) | FDFT1 | |
| SCHEMBL8272194 | 0.81 | FDFT1 (0.35) | FDFT1 | |
| SCHEMBL8272196 | 0.77 | TP53 (0.40) | FDFT1 | |
| SCHEMBL8272848 | 0.76 | PKM (0.44) | FDFT1 | |
| SCHEMBL3252395 | 0.74 | KEAP1 (0.52) | FDFT1 | |
| SCHEMBL4872059 | 0.74 | KEAP1 (0.52) | FDFT1 | |
| SCHEMBL3253822 | 0.73 | PKM (0.49) | FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776347-B1 | SULPHONAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI AVENTIS (FR) | 2010-05-26 | — | — | EP | disclosed |
| WO-2006024779-A1 | SULPHONAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI-AVENTIS (FR) | 2006-03-09 | — | — | WO | disclosed |