SCHEMBL827288

SCHEMBL827288

[c]1ccccc1C/C=C/c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.41
PAM P19021 1/20 0.41
PTGER4 P35408 1/20 0.39
PTGER3 P43115 1/20 0.39
PTGER2 P43116 1/20 0.39
HTR2A P28223 3/20 0.39
SIGMAR1 Q99720 2/20 0.39
MAOB P27338 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
RECQL P46063 1/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
ALOX15 P16050 1/20 0.36
CHAT P28329 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5542626 1.00 IDO1 (0.41) IDO1PAMPTGER4PTGER3PTGER2
SCHEMBL482877 0.76 MAOB (0.30) MAOB
SCHEMBL9199675 0.76 MAOB (0.30) MAOB
SCHEMBL482794 0.76 MAOB (0.30) MAOB
SCHEMBL3515158 0.76 MAOB (0.30) MAOB
SCHEMBL1069078 0.74 MAOB (0.33) MAOB
SCHEMBL294593 0.74 MAOB (0.33) MAOB
SCHEMBL6067510 0.73
SCHEMBL2701351 0.73
SCHEMBL2701350 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8420141-B2 Food coloring PEPSICO, INC. (US) 2013-04-16 US claimed
US-20070110851-A1 Beverage composition and method of preventing degradation of vitamins in beverages PEPSICO, INC. 2007-05-17 US claimed
EP-1782701-A1 Beverage composition and method of preventing degradation of vitamins in beverages PepsiCo, Inc. (US) 2007-05-09 EP claimed
US-20040198741-A1 Compounds, compositions and methods for treating or preventing viral infections and associated diseases WYETH 2004-10-07 US claimed
US-20040091589-A1 Prevention of synthetic color fading in beverages using botanically derived color stabilizers PEPSICO, INC. 2004-05-13 US claimed
US-20030195213-A1 Compounds, compositions and methods for treating or preventing viral infections and associated diseases BAILEY THOMAS R (US) 2003-10-16 US claimed
EP-1128832-A4 COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING VIRAL INFECTIONS AND ASSOCIATED DISEASES VIROPHARMA INC (US) 2003-03-05 EP claimed
EP-1128832-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING VIRAL INFECTIONS AND ASSOCIATED DISEASES Viropharma Incorporated (US) 2001-09-05 EP claimed
WO-2000010573-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING VIRAL INFECTIONS AND ASSOCIATED DISEASES VIROPHARMA INCORPORATED (US) 2000-03-02 WO claimed
US-11781037-B2 High-durability antifogging coating film and coating composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-10-10 US disclosed
CN-116143660-A Compound, curing agent composition, resin composition, coating composition, and resin cured product 旭化成株式会社 2023-05-23 CN disclosed
US-20230086403-A1 LAMINATE, HARD COATING FILM, AND COATING MATERIAL COMPOSITION ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-03-23 US disclosed
EP-4116085-A1 LAMINATE, HARD-COAT COATING FILM, AND COATING MATERIAL COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2023-01-11 EP disclosed
CN-111684030-B High-durability antifogging coating film and coating composition 旭化成株式会社 2022-11-01 CN disclosed
US-20060287527-A1 Process for producing acrylic acid derivative NIPPON SODA CO., LTD. (JP) 2006-12-21 US disclosed
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-05-04 US disclosed
EP-1555267-A1 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-07-20 EP disclosed
US-20040152894-A1 Process for producing acrylic acid derivative NIPPON SODA CO. LTD (JP) 2004-08-05 US disclosed
US-20040091589-A1 Prevention of synthetic color fading in beverages using botanically derived color stabilizers PEPSICO, INC. 2004-05-13 US disclosed
EP-1142857-A1 PROCESSES FOR PRODUCING ACRYLIC ACID DERIVATIVE NIPPON SODA CO., LTD. (JP) 2001-10-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040152894-A1 Process for producing acrylic acid derivative OXGR1, GART, HAO2 IDO1 3478/4885PAM 300/4885PTGER4 2516/4885
US-20030195213-A1 Compounds, compositions and methods for treating or preventing viral infections and associated diseases RXRG, TREH, RARG IDO1 1838/4885PAM 1686/4885PTGER4 2569/4885
US-20060094767-A1 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles NR2C2, NR4A3, NR4A2 IDO1 3181/4885PAM 1855/4885PTGER4 3830/4885
US-20040198741-A1 Compounds, compositions and methods for treating or preventing viral infections and associated diseases RXRG, TREH, RARG IDO1 1838/4885PAM 1686/4885PTGER4 2569/4885
US-20060287527-A1 Process for producing acrylic acid derivative APEH, HAAO, ASNS IDO1 3753/4885PAM 417/4885PTGER4 2858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.