Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28073256 | 0.90 | MEN1 (0.50) | MEN1KMT2ANAMPTMAPK1OPRD1 | |
| SCHEMBL17001691 | 0.85 | MEN1 (0.61) | MEN1KMT2ANAMPTMAPK1OPRD1 | |
| SCHEMBL30550841 | 0.85 | MEN1 (0.61) | MEN1KMT2ANAMPTMAPK1OPRD1 | |
| SCHEMBL19056599 | 0.84 | MEN1 (0.51) | MEN1KMT2ANAMPTMAPK1OPRD1 | |
| SCHEMBL4857225 | 0.83 | MEN1 (0.48) | MEN1KMT2ANAMPTMAPK1OPRD1 | |
| SCHEMBL4858860 | 0.82 | MEN1 (0.50) | MEN1KMT2ANAMPTMAPK1OPRD1 | |
| SCHEMBL11929939 | 0.81 | MEN1 (0.49) | MEN1KMT2ANAMPTMAPK1OPRD1 | |
| SCHEMBL26793670 | 0.81 | MEN1 (0.51) | MEN1KMT2ANAMPTMAPK1OPRD1 | |
| SCHEMBL11929926 | 0.79 | MTNR1B (0.47) | MEN1KMT2APRMT5WDR77UCHL1 | |
| SCHEMBL30428702 | 0.78 | MEN1 (0.46) | MEN1KMT2ANAMPTMAPK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |