Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22065919 | 0.86 | CLK1 (0.37) | KDM4EACHEKDM4CHTTPARP1 | |
| SCHEMBL22744586 | 0.80 | SSTR4 (0.51) | IMPDH2CYP1A2CYP3A4CYP2C19KDM4E | |
| SCHEMBL3968484 | 0.77 | IDO1 (0.44) | IMPDH2LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8274137 | 0.72 | IDO1 (0.40) | IMPDH2LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3971384 | 0.70 | KDM4E (0.43) | IMPDH2LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL445595 | 0.70 | IMPDH2 (0.58) | IMPDH2LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22065129 | 0.69 | IL5 (0.46) | CYP1A2ACHEPARP1 | |
| SCHEMBL8276161 | 0.68 | CYP2A6 (0.34) | PARP1 | |
| SCHEMBL15665250 | 0.68 | PARP1 (0.36) | KDM4CPARP1 | |
| SCHEMBL1536439 | 0.68 | LMNA (0.41) | LMNACYP3A4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006000085-A1 | HEPATITIS C INHIBITOR PEPTIDE ANALOGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-01-05 | — | — | WO | disclosed |