Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8274276 | 1.00 | CTSL (0.52) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL13869038 | 0.83 | ALDH1A1 (0.49) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL27876084 | 0.82 | LMNA (0.54) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL3361808 | 0.79 | LMNA (0.61) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL4462583 | 0.79 | LMNA (0.61) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL27016034 | 0.79 | ALDH1A1 (0.51) | CTSLCTSBCTSSCTSKALDH1A1 | |
| Acetic Acid SCHEMBL8324881 | 0.79 | LMNA (0.56) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL5543236 | 0.77 | LMNA (0.62) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL8274260 | 0.76 | SMN1; SMN2 (0.48) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL8274274 | 0.76 | SMN1; SMN2 (0.48) | CTSLCTSBCTSSCTSKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005111009-A2 | SYNTHESIS OF AMINO ACID KETO-EPOXIDES | PROTEOLIX, INC. (US) | 2005-11-24 | — | — | WO | disclosed |