Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | UNG | P13051 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 4/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13915486 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNAALDH1A1L3MBTL1CYP26A1 | |
| SCHEMBL8274382 | 0.81 | SRC (0.47) | SMN1; SMN2LMNAALDH1A1CYP26B1NPC1 | |
| SCHEMBL18590254 | 0.80 | LMNA (0.50) | SMN1; SMN2LMNARAB9ARECQL | |
| SCHEMBL13468797 | 0.78 | NPC1 (0.58) | SMN1; SMN2LMNAALDH1A1L3MBTL1NPC1 | |
| SCHEMBL8459424 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1L3MBTL1UNGNPC1 | |
| SCHEMBL13469226 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1L3MBTL1UNGNPC1 | |
| SCHEMBL18767289 | 0.75 | HDAC4 (0.40) | SMN1; SMN2LMNANPC1RAB9AKMT2A | |
| SCHEMBL5407676 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAALDH1A1L3MBTL1NPC1 | |
| SCHEMBL13351520 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAALDH1A1L3MBTL1NPC1 | |
| SCHEMBL15614329 | 0.74 | ALDH1A1 (0.42) | SMN1; SMN2LMNAALDH1A1L3MBTL1UNG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090076088-A1 | Thrombin Receptor Antagonists | SCHERING CORPORATION | 2009-03-19 | — | — | US | disclosed |
| US-20090069383-A1 | Thrombin Receptor Antagonists | SCHERING CORPORATION | 2009-03-12 | — | — | US | disclosed |
| US-7488742-B2 | Thrombin receptor antagonists | SCHERING CORPORATION (US) | 2009-02-10 | — | — | US | disclosed |
| US-20040152736-A1 | Thrombin receptor antagonists | TOPROL ACQUISITION LLC | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076088-A1 | Thrombin Receptor Antagonists | CNR1, CNR2, TBXA2R | SMN1; SMN2 4636/4885LMNA 2394/4885ALDH1A1 3883/4885 |
| US-20040152736-A1 | Thrombin receptor antagonists | CNR1, TBXA2R, CNR2 | SMN1; SMN2 4388/4885LMNA 2885/4885ALDH1A1 3033/4885 |
| US-20090069383-A1 | Thrombin Receptor Antagonists | CNR1, CNR2, TBXA2R | SMN1; SMN2 4636/4885LMNA 2394/4885ALDH1A1 3883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.