SCHEMBL827467

SCHEMBL827467

C=CC(=O)CCCCOc1ccc(C(=O)Oc2ccc(OC(=O)c3ccc(OCCCCC(=O)C=C)cc3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.51
NPC1 O15118 3/20 0.51
CYP1A2 P05177 2/20 0.51
CYP2C9 P11712 2/20 0.51
CYP2C19 P33261 2/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
NFKB1 P19838 3/20 0.50
NFKB2 Q00653 3/20 0.50
RELA Q04206 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
PRSS1 P07477 1/20 0.48
ACR P10323 1/20 0.48
MAPT P10636 3/20 0.47
KMT2A Q03164 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ALDH1A1 P00352 1/20 0.47
PPARA Q07869 1/20 0.46
GAA P10253 1/20 0.45
HTT P42858 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5485757 0.95 LMNA (0.47) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL8966828 0.92 LMNA (0.50) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL14370292 0.92 MAPT (0.56) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL14484202 0.92 NPC1 (0.50) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL14426402 0.92 NPC1 (0.50) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL13934493 0.91 HTT (0.47) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL17279027 0.91 HTT (0.47) LMNANPC1CYP1A2CYP2C9CYP2C19
SCHEMBL2107828 0.85 ALDH1A1 (0.65) L3MBTL1ALDH1A1PPARAHTTPOLB
SCHEMBL9013276 0.85 PPARA (0.44) LMNANPC1NFKB1NFKB2RELA
SCHEMBL14601542 0.84 MAPT (0.43) LMNANPC1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142682-B2 Cholesteric multi-layers SICPA HOLDING SA (CH) 2012-03-27 US disclosed
US-7794620-B2 Cholesteric monolayers and monolayer pigments with particular properties, their production and use SICPA HOLDING S.A. (CH) 2010-09-14 US disclosed
EP-2032672-B1 CHOLESTERIC MULTI-LAYERS SICPA HOLDING SA (CH) 2010-09-01 EP disclosed
US-20100178508-A1 Cholesteric Multi-Layers SICPA HOLDING S.A. (CH) 2010-07-15 US disclosed
EP-2032672-A1 CHOLESTERIC MULTI-LAYERS Sicpa Holding S.A. (CH) 2009-03-11 EP disclosed
US-20080305315-A1 Cholesteric Monolayers and Monolayer Pigments with Particular Properties, Their Production and Use SICPA HOLDING S.A. (CH) 2008-12-11 US disclosed
US-7396486-B2 Polymerizable mixtures WACKER CHEMIE AG (DE) 2008-07-08 US disclosed
EP-1831328-B1 CHOLESTERIC MONOLAYERS AND MONOLAYER PIGMENTS WITH PARTICULAR PROPERTIES, THEIR PRODUCTION AND USE SICPA HOLDING SA (CH) 2008-05-14 EP disclosed
EP-1876216-A1 Cholesteric multi-layers Sicpa Holding S.A. (CH) 2008-01-09 EP disclosed
WO-2008000755-A1 CHOLESTERIC MULTI-LAYERS SICPA HOLDING S.A. (CH) 2008-01-03 WO disclosed
EP-1558699-B1 POLYMERISABLE MIXTURES CONSORTIUM ELEKTROCHEM IND (DE) 2006-04-05 EP disclosed
EP-1558699-A1 POLYMERISABLE MIXTURES Consortium für elektrochemische Industrie GmbH (DE) 2005-08-03 EP disclosed
WO-2004041966-A1 POLYMERISABLE MIXTURES Consortium für elektrochemische Industrie GmbH (DE) 2004-05-21 WO disclosed
US-6732961-B2 MATERIAL TO BE PROCESSED INTO PLATELETS IS APPLIED IN A FLOWABLE OR GASEOUS STATE TO A SUBSTRATE, CONSOLIDATED, REMOVED FROM SUBSTRATE, AND SUBJECTED TO CRUSHING OR GRINDING, WHEREIN MATERIAL IS APPLIED IN SUCCEEDING LAYERS CONSORTIUM FUER ELEKTROCHEMISCHE INDUSTRIE, GMBH (DE) 2004-05-11 US disclosed
EP-1213338-B1 Methods for preparing flakes CONSORTIUM ELEKTROCHEM IND (DE) 2003-07-23 EP disclosed
EP-1046692-B1 Thermostable pigments, films, effect coatings and mixtures for their preparation CONSORTIUM ELEKTROCHEM IND (DE) 2002-08-07 EP disclosed
US-6423246-B1 LIQUID CRYSTAL POLYMERS AND CROSSLINKING CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 2002-07-23 US disclosed
US-20020086113-A1 Method of producing platelets CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 2002-07-04 US disclosed
EP-1213338-A1 Methods for preparing flakes Consortium für elektrochemische Industrie GmbH (DE) 2002-06-12 EP disclosed
EP-1046692-A1 Thermostable pigments, films, effect coatings and mixtures for their preparation Consortium für elektrochemische Industrie GmbH (DE) 2000-10-25 EP disclosed