SCHEMBL8275

SCHEMBL8275

C1=NSc2ccccc2C1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RYR2 Q92736 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6424274 0.98 RYR2 (0.31) RYR2
SCHEMBL7687194 0.78
SCHEMBL7352569 0.78 TSHR (0.32)
SCHEMBL4488571 0.75
SCHEMBL720559 0.67 ALDH1A1 (0.42) KDM4EALDH1A1HPGD
SCHEMBL7845462 0.67 KDM4E (0.34) KDM4EALDH1A1HPGD
SCHEMBL9079908 0.67
SCHEMBL7837771 0.67 KDM4E (0.34) KDM4EALDH1A1HPGD
SCHEMBL8034880 0.67 BCL2L1 (0.34) ALDH1A1HPGD
SCHEMBL11807290 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4136 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122005810-A Application of peroxide reductase 1 as target in preparation of IS therapeutic drugs 国科宁波生命与健康产业研究院 2026-05-12 CN claimed
EP-4630043-A1 IMMUNE-ACTIVATING COMPLEXES Dynamic Cell Therapies, Inc. (US) 2025-10-15 EP claimed
EP-4630446-A1 ENGINEERED SWITCHES FOR IMMUNE CELL ACTIVITY AND METHODS OF USE THEREOF Dynamic Cell Therapies, Inc. (US) 2025-10-15 EP claimed
CN-116970145-B Amphiphilic triblock polymer, stimulus-responsive nanoparticle and preparation method thereof 中国科学技术大学 2025-06-13 CN claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
CN-120020131-A Aromatic ring benzothiazine derivative and medical application thereof 杭州百诚医药科技股份有限公司 2025-05-20 CN claimed
CN-119745702-A Zirconia ceramic block for manufacturing false tooth 深圳玉汝成口腔材料有限公司 2025-04-04 CN claimed
CN-119744352-A Intracellular ligation of photocatalysts for photoresponsive, probe-mediated protein labeling 美国锡德治疗有限公司 2025-04-01 CN claimed
CN-119504645-A Method for synthesizing N- (acetamidomethyl) benzothiazine-4-ketone 常州大学 2025-02-25 CN claimed
US-20250057874-A1 SYNTHETIC MELANIN NANOPARTICLES AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-20 US claimed
EP-0140886-A4 FILM BADGE FOR DETERMINING CARBONYL COMPOUNDS. LITTLE INC A (US) 1985-09-02 EP claimed
EP-0079639-B1 A NEW ANTI-INFLAMMATORY DRUG SPA SOCIETA' PRODOTTI ANTIBIOTICI S.p.A. (IT) 1985-07-24 EP claimed
EP-0042435-B1 BENZOTHIAZINE DERIVATIVES Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1985-06-12 EP claimed
EP-0140886-A1 FILM BADGE FOR DETERMINING CARBONYL COMPOUNDS. LITTLE INC A (US) 1985-05-15 EP claimed
US-4490292-A 1,5-Benzothiazepine derivatives and production thereof HAMARI CHEMICALS, LTD. (JP) 1984-12-25 US claimed
WO-1984004165-A1 FILM BADGE FOR DETERMINING CARBONYL COMPOUNDS LITTLE INC A (US) 1984-10-25 WO claimed
US-4434163-A Water-soluble benzothiazine dioxide salts PFIZER INC. (US) 1984-02-28 US claimed
US-4434164-A AMINE SALTS OF N-/2-PYRIDYL/-2-METHYL-4-HYDROXY--2H-1,2-BENZOTHIAZINE-3-CARBOXAMIDE,-1,1 -DIOXIDE PFIZER INC. (US) 1984-02-28 US claimed
EP-0042435-A1 BENZOTHIAZINE DERIVATIVES Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1981-12-30 EP claimed
US-4294961-A REMOVAL OF METALS HENKEL CORPORATION (US) 1981-10-13 US claimed