Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | BAD | Q92934 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPN | P05981 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6675187 | 0.71 | CYP1A2 (0.40) | ALDH1A1HSD17B10MEN1CYP3A4MAPT | |
| SCHEMBL8275 | 0.67 | RYR2 (0.31) | ALDH1A1HPGD | |
| SCHEMBL8583239 | 0.67 | BCL2L1 (0.44) | BCL2L1BADALDH1A1ALOX15HSD17B10 | |
| SCHEMBL4350460 | 0.65 | BCL2L1 (0.38) | BCL2L1BADALDH1A1ALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL6424274 | 0.65 | RYR2 (0.31) | — | |
| SCHEMBL17058346 | 0.64 | — | — | |
| SCHEMBL8038664 | 0.63 | DRD2 (0.33) | ALDH1A1HSD17B10LMNA | |
| SCHEMBL8034883 | 0.61 | BCL2L1 (0.38) | BCL2L1BADALDH1A1ALOX15HSD17B10 | |
| SCHEMBL8034887 | 0.61 | BCL2L1 (0.34) | BCL2L1BADALDH1A1ALOX15HSD17B10 | |
| SCHEMBL9079908 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661039-B1 | Oxidative hair dyeing method, composition and kit utilizing hydroxyl substituted benzothiazines | BRISTOL MYERS SQUIBB CO (US) | 2000-04-05 | — | — | EP | disclosed |
| EP-0661039-A1 | Oxidative hair dyeing method, composition and kit utilizing hydroxyl substituted benzothiazines | Bristol-Myers Squibb Company (US) | 1995-07-05 | — | — | EP | disclosed |
| US-5374288-A | Oxidative hair dyeing method, composition, and kit utilizing hydroxyl substituted benzothiazines | CLAIROL INCORPORATED (US) | 1994-12-20 | — | — | US | disclosed |