Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 3/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1444506 | 0.90 | LMNA (0.43) | LMNASLC1A3SLC1A2SLC1A1TDP1 | |
| SCHEMBL12446343 | 0.86 | LMNA (0.38) | LMNASLC1A3SLC1A2SLC1A1PTGIR | |
| SCHEMBL23129641 | 0.81 | LMNA (0.57) | LMNASLC1A3SLC1A2SLC1A1PARP15 | |
| SCHEMBL1672623 | 0.80 | LMNA (0.55) | LMNASLC1A3SLC1A2SLC1A1PARP15 | |
| SCHEMBL25381860 | 0.80 | LMNA (0.50) | LMNASLC1A3SLC1A2SLC1A1PARP15 | |
| SCHEMBL5988042 | 0.79 | LMNA (0.37) | LMNASLC1A3SLC1A2SLC1A1PTGIR | |
| SCHEMBL697741 | 0.79 | LMNA (0.37) | LMNASLC1A3SLC1A2SLC1A1PTGIR | |
| SCHEMBL697012 | 0.79 | LMNA (0.37) | LMNASLC1A3SLC1A2SLC1A1PTGIR | |
| SCHEMBL1439642 | 0.79 | ALDH1A1 (0.59) | LMNAALDH1A1 | |
| SCHEMBL1669840 | 0.78 | LMNA (0.59) | LMNASLC1A3SLC1A2SLC1A1PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2316839-B1 | ANTIVIRAL HETEROCYCLIC COMPOUNDS HAVING PHOSPHONATE GROUPS | GILEAD SCIENCES INC (US) | 2014-03-12 | — | — | EP | disclosed |
| WO-2006020276-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2006-02-23 | — | — | WO | disclosed |