Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP1 | P63208 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8224033 | 0.89 | CHRM4 (0.44) | PIK3CBNR1H4LMNAHTTKDM4E | |
| SCHEMBL8273636 | 0.83 | ALDH1A1 (0.39) | HTTKDM4EPOLBALDH1A1L3MBTL1 | |
| SCHEMBL8273638 | 0.83 | ALDH1A1 (0.38) | HTTKDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL8273643 | 0.83 | ALDH1A1 (0.38) | HTTKDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL8275485 | 0.83 | CKS1B (0.39) | KDM4EALDH1A1L3MBTL1SMN1; SMN2CKS1B | |
| SCHEMBL8273633 | 0.83 | CKS1B (0.41) | KDM4EALDH1A1L3MBTL1SMN1; SMN2CKS1B | |
| SCHEMBL8273640 | 0.82 | ALDH1A1 (0.38) | HTTKDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL8273635 | 0.81 | CKS1B (0.37) | KDM4EALDH1A1L3MBTL1CKS1BSKP1 | |
| SCHEMBL8276134 | 0.80 | ADAM17 (0.37) | HTTKDM4EALDH1A1L3MBTL1CKS1B | |
| SCHEMBL8273641 | 0.76 | RPS6KB1 (0.39) | HTTKDM4EALDH1A1L3MBTL1CKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |