Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 3/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8273641 | 0.89 | RPS6KB1 (0.39) | ADAM17KMT2ARPS6KB1CKS1BSKP1 | |
| SCHEMBL8215266 | 0.88 | CHRM4 (0.47) | ADAM17RPS6KB1SCN5ASCN9A | |
| SCHEMBL8273636 | 0.81 | ALDH1A1 (0.39) | ADAM17RPS6KB1CKS1BSKP1SKP2 | |
| SCHEMBL8273633 | 0.80 | CKS1B (0.41) | RPS6KB1CKS1BSKP1SKP2ALDH1A1 | |
| SCHEMBL8273638 | 0.80 | ALDH1A1 (0.38) | ADAM17RPS6KB1CKS1BSKP1SKP2 | |
| SCHEMBL8275481 | 0.80 | PIK3CB (0.43) | CKS1BSKP1SKP2ALDH1A1GAA | |
| SCHEMBL8273640 | 0.79 | ALDH1A1 (0.38) | ADAM17RPS6KB1CKS1BSKP1SKP2 | |
| SCHEMBL8276118 | 0.79 | ADAM17 (0.43) | ADAM17MEN1KMT2AALDH1A1GAA | |
| SCHEMBL8274407 | 0.79 | ADAM17 (0.43) | ADAM17MEN1KMT2AALDH1A1GAA | |
| SCHEMBL8275981 | 0.79 | NAMPT (0.42) | ADAM17RPS6KB1ALDH1A1L3MBTL1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |