Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8222034 | 0.89 | ADAM17 (0.43) | ADAM17MEN1KMT2ANAMPTCHRM4 | |
| SCHEMBL8273743 | 0.85 | ADAM17 (0.46) | ADAM17MEN1KMT2ANAMPTALDH1A1 | |
| SCHEMBL13544350 | 0.82 | ADAM17 (0.47) | ADAM17MEN1KMT2ANAMPT | |
| SCHEMBL14494381 | 0.81 | ADAM17 (0.43) | ADAM17MEN1KMT2ANAMPTCHRM4 | |
| SCHEMBL8273765 | 0.81 | ADAM17 (0.43) | ADAM17MEN1KMT2ANAMPTCHRM4 | |
| SCHEMBL8217012 | 0.80 | HTR1A (0.47) | ADAM17MEN1KMT2ANAMPTALDH1A1 | |
| SCHEMBL8220831 | 0.80 | ADAM17 (0.46) | ADAM17MEN1KMT2ANAMPTKDM4E | |
| SCHEMBL8221017 | 0.80 | ADAM17 (0.42) | ADAM17MEN1KMT2ANAMPTALDH1A1 | |
| SCHEMBL8276118 | 0.80 | ADAM17 (0.43) | ADAM17MEN1KMT2ANAMPTALDH1A1 | |
| SCHEMBL8274407 | 0.80 | ADAM17 (0.43) | ADAM17MEN1KMT2ANAMPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |