Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8275985 | 0.91 | MEN1 (0.41) | NAMPTMTNR1AMTNR1BALDH1A1HPGD | |
| SCHEMBL8415560 | 0.88 | ADAM17 (0.40) | NAMPTMTNR1AMTNR1BALDH1A1MEN1 | |
| SCHEMBL8223637 | 0.87 | NAMPT (0.39) | NAMPTMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL8223144 | 0.84 | NAMPT (0.47) | NAMPTALDH1A1MEN1KMT2ANOTUM | |
| SCHEMBL8275947 | 0.83 | ADAM17 (0.47) | NAMPTMTNR1AMTNR1BALDH1A1HPGD | |
| SCHEMBL8276821 | 0.81 | ADAM17 (0.42) | NAMPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL8213997 | 0.81 | NAMPT (0.37) | NAMPTMTNR1AMTNR1BALDH1A1HPGD | |
| SCHEMBL8415324 | 0.79 | ADAM17 (0.47) | NAMPTALDH1A1MEN1KMT2A | |
| SCHEMBL8216981 | 0.78 | MEN1 (0.38) | NAMPTMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL8220841 | 0.77 | MEN1 (0.39) | NAMPTMEN1KMT2ADPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |