Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31129062 | 0.98 | KMT2A (0.49) | ATML3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL30964113 | 0.84 | POLB (0.64) | L3MBTL1ALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL9158848 | 0.83 | HPGD (0.42) | ATML3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL25771063 | 0.77 | KMT2A (0.51) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL25148205 | 0.77 | POLB (0.55) | L3MBTL1ALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL17576885 | 0.77 | GLA (0.54) | ATML3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL644646 | 0.77 | TSHR (0.45) | TDP1ALDH1A1TSHR | |
| SCHEMBL23119464 | 0.76 | EPHX2 (0.50) | ALDH1A1SMN1; SMN2TSHRHPGD | |
| SCHEMBL12014400 | 0.76 | ALDH1A1 (0.48) | L3MBTL1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL13672719 | 0.76 | ATM (0.52) | ATML3MBTL1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |